Alexander Kreuter Selected Research

Fibrosis (Cirrhosis)

4/2024	Combined inhibition of IL-1, IL-33 and IL-36 signalling by targeting IL1RAP ameliorates skin and lung fibrosis in preclinical models of systemic sclerosis.
3/2024	Attenuation of fibroblast activation and fibrosis by adropin in systemic sclerosis.
3/2024	Noncanonical WNT5A controls the activation of latent TGF-β to drive fibroblast activation and tissue fibrosis.
12/2023	Anti-S100A4 monoclonal antibody treatment ameliorates experimental skin fibrosis and SSc-specific transcriptional signatures in human skin.
1/2021	X-linked inhibitor of apoptosis protein (XIAP) inhibition in systemic sclerosis (SSc).
1/2019	Acyltransferase skinny hedgehog regulates TGFβ-dependent fibroblast activation in SSc.
1/2018	The histone demethylase Jumonji domain-containing protein 3 (JMJD3) regulates fibroblast activation in systemic sclerosis.
5/2015	Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis.
12/2012	Influence of the IL6 gene in susceptibility to systemic sclerosis.
3/2012	Localized scleroderma.

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Alexander Kreuter Research Topics

Disease

29	Systemic Scleroderma (Systemic Sclerosis) 04/2024 - 05/2004
26	Neoplasms (Cancer) 05/2024 - 06/2004
17	Melanoma (Melanoma, Malignant) 10/2023 - 05/2009
12	Fibrosis (Cirrhosis) 04/2024 - 11/2009
11	Localized Scleroderma (Morphea) 03/2024 - 02/2002
8	Skin Diseases (Skin Disease) 03/2024 - 02/2002
8	Cutaneous Lupus Erythematosus 04/2022 - 09/2004
7	Skin Neoplasms (Skin Cancer) 03/2024 - 05/2021
7	Neoplasm Metastasis (Metastasis) 10/2023 - 05/2009
7	Lichen Sclerosus et Atrophicus (Lichen Sclerosus) 07/2013 - 02/2002
6	Psoriasis (Pustulosis Palmaris et Plantaris) 12/2023 - 04/2005
6	Nephrogenic Fibrosing Dermopathy 01/2012 - 11/2008
5	Atopic Dermatitis (Atopic Eczema) 12/2023 - 08/2002
4	Pyoderma Gangrenosum 10/2023 - 03/2005
4	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 01/2023 - 04/2005
4	Inflammation (Inflammations) 10/2014 - 08/2002
4	Infections 04/2014 - 08/2008
3	Bronchiolitis Obliterans Syndrome 04/2024 - 03/2024
3	Brain Neoplasms (Brain Tumor) 01/2023 - 01/2020
3	Disease Progression 07/2021 - 11/2009
3	Carcinoma (Carcinomatosis) 02/2021 - 07/2008
3	Anus Neoplasms (Anal Cancer) 12/2020 - 04/2009
3	Lymphoma (Lymphomas) 10/2020 - 01/2006
3	Pain (Aches) 02/2016 - 10/2004
3	Ulcer 10/2013 - 07/2008
3	Dysplastic Nevus Syndrome (Dysplastic Nevus) 06/2009 - 05/2009
3	Erythema 03/2009 - 10/2004
2	Pulmonary Fibrosis (Fibrosing Alveolitis) 04/2024 - 03/2024
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 03/2024 - 01/2014
2	Basal Cell Carcinoma (Rodent Ulcer) 03/2024 - 04/2022
2	Livedoid Vasculopathy 02/2016 - 10/2004
2	Carcinogenesis 05/2015 - 09/2004
2	Connective Tissue Diseases (Connective Tissue Disease) 04/2015 - 09/2004
2	Dermatitis 11/2014 - 07/2013
2	Pruritus (Itching) 06/2014 - 09/2006
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 07/2013 - 01/2013
2	T-Cell Lymphoma (Lymphoma, T Cell) 05/2013 - 12/2005
2	Leg Ulcer 11/2012 - 01/2011
2	Mucinoses 06/2012 - 06/2011
2	Calciphylaxis 12/2011 - 03/2009
2	Nausea 06/2011 - 03/2009
2	Keloid 05/2011 - 02/2007
2	HIV Infections (HIV Infection) 04/2011 - 12/2006
2	Nevus (Nevi) 06/2009 - 05/2009

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 01/2021 - 03/2005
9	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 02/2006
8	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2023 - 03/2002
8	Messenger RNA (mRNA)IBA 11/2012 - 10/2006
7	Bleomycin (Blenoxane)FDA LinkGeneric 04/2024 - 05/2015
7	Immune Checkpoint InhibitorsIBA 10/2023 - 01/2016
6	CytokinesIBA 04/2024 - 09/2008
6	Biomarkers (Surrogate Marker)IBA 10/2023 - 09/2010
5	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2023 - 01/2018
5	Imiquimod (Aldara)FDA LinkGeneric 08/2008 - 06/2004
4	CollagenIBA 12/2023 - 05/2004
4	Indicators and Reagents (Reagents)IBA 01/2022 - 05/2011
4	Transforming Growth Factor beta (TGF-beta)IBA 01/2018 - 10/2006
4	GadoliniumIBA 01/2012 - 10/2009
4	Contrast MediaIBA 01/2012 - 10/2009
3	Type I DNA Topoisomerases (Topoisomerase I)IBA 04/2024 - 01/2018
3	AntibodiesIBA 04/2024 - 03/2013
3	Papillomavirus Vaccines (HPV Vaccines)IBA 02/2021 - 01/2011
3	Interleukin-6 (Interleukin 6)IBA 12/2012 - 09/2008
3	Antimicrobial PeptidesIBA 11/2012 - 01/2008
3	pimecrolimus (Elidel)FDA Link 09/2006 - 09/2004
3	Intravenous Immunoglobulins (IVIG)FDA Link 01/2005 - 10/2004
2	Interleukin-33IBA 04/2024 - 01/2013
2	Interleukin-1 (Interleukin 1)IBA 04/2024 - 11/2012
2	LigandsIBA 03/2024 - 05/2012
2	Monoclonal AntibodiesIBA 12/2023 - 06/2009
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2023 - 09/2008
2	AcidsIBA 01/2023 - 12/2022
2	Bendamustine Hydrochloride FDA Link 01/2023 - 10/2020
2	pembrolizumabIBA 04/2022 - 01/2022
2	NivolumabIBA 01/2022 - 09/2019
2	IpilimumabIBA 01/2022 - 01/2016
2	AutoantibodiesIBA 04/2015 - 03/2013
2	InterferonsIBA 10/2014 - 01/2006
2	Anti-Bacterial Agents (Antibiotics)IBA 10/2013 - 03/2009
2	Interleukin-2 (IL2)IBA 07/2013 - 09/2008
2	Adenosine Monophosphate (AMP)IBA 11/2012 - 07/2011
2	Interleukin-8 (Interleukin 8)IBA 11/2012 - 09/2008
2	Interleukin-10 (Interleukin 10)IBA 11/2012 - 09/2008
2	FumaratesIBA 07/2012 - 03/2002
2	Antimalarials (Antimalarial Agents)IBA 06/2011 - 03/2009
2	Methotrexate (Mexate)FDA LinkGeneric 11/2009 - 07/2005
2	DecorinIBA 07/2009 - 06/2007
2	ParaffinIBA 05/2009 - 05/2009

Therapy/Procedure

45	Therapeutics 03/2024 - 02/2002
18	Phototherapy (Light Therapy) 06/2014 - 02/2002
5	Radiotherapy 05/2024 - 04/2015
5	Photopheresis 11/2023 - 04/2005
4	Chemoradiotherapy 12/2020 - 04/2009
4	Renal Dialysis (Hemodialysis) 01/2012 - 03/2009
3	Immunotherapy 10/2023 - 01/2016
2	Maggot Debridement Therapy 10/2023 - 10/2023
2	Photochemotherapy (Photodynamic Therapy) 12/2022 - 09/2004
2	Stem Cell Transplantation 01/2014 - 05/2013
2	Transplantation 01/2014 - 01/2011
2	Highly Active Antiretroviral Therapy (HAART) 04/2009 - 12/2006